After being nearly killed during a violent fight with a powerful drug lord, a Mexican Federale known as Machete (Danny Trejo) roams Texas streets as a vigilante and sometime day-laborer. Hired by a corrupt senator to perform a covert hit, Machete is double-crossed and forced to go on the run. Machete may be down, but not out, and he carves a path of blood, bullets and broken hearts in a mission to settle the score.