Pin It
Favorite

Forbidden Fruit 

Pill Box

I just picked up my prescription for lovastatin. My pharmacist warned me not to drink grapefruit juice while taking this medication. Why? Can I drink orange juice instead?

click to enlarge John R. White chairs WSU-Spokane's Department of Pharmacotherapy.
  • John R. White chairs WSU-Spokane's Department of Pharmacotherapy.

The grapefruit juice warning is real and should be heeded! The food-drug interactions with grapefruit juice result in more of the active medication getting into your system. In the case of lovastatin and grapefruit juice, taking the two together can provide an amount of lovastatin to your body that is equivalent to consuming 15 doses of lovastatin without grapefruit juice. This can result in significant toxicity.

Many medications undergo this interaction, including some over-the-counter medications like dextromethorphan (found in Robitussin). Some grapefruit juice-drug interactions are worse than others and not all people respond in the same fashion. Also, there are differences in the interaction between different types of grapefruit juice.

However, if the medication label or the pharmacist recommends "do not take with grapefruit juice" then you shouldn't. Except for Seville or bitter orange juice, which is a specialty item not commonly consumed in the U.S., regular orange juice does not cause this interaction and is fine.

Pin It
Favorite

Tags:

Readers also liked…

Today | Thu | Fri | Sat | Sun | Mon | Tue
Il•lu•mi•na•tion Gallery Show

Il•lu•mi•na•tion Gallery Show @ Terrain

Thursdays-Saturdays. Continues through Dec. 29

All of today's events | Staff Picks

More by John R. White

Top Tags in
Health & Home

Health & Home


Food


WSU


health


art


CDA


© 2018 Inlander
Website powered by Foundation